Sunday, February 13, 2022

Whole Bibit Sequencing

In selecting spouse, Javanese teaching uses the measurement of Bibit (consider his/her family background and good name), Bobot (consider his/her good education and strong morals) and Bebet (Javanese is a paternalistic society, hence, the wife should consider that her prospective husband can be relied as a breadwinner/provider for the family). This teaching -in particular the Bibit- popped out in my head while listening a podcast that discussed about genetic engineering.  The dropping of  the cost of whole-genome sequencing would soon allow us to analyze the genetic of the potential mates to check for his/her genetic defect (and of course his/her superiorities if any)

It wouldn't hard to imagine a scenario where our saliva is unknowingly collected to be sent to a lab for a rapid analysis that would mapped out all there are about our genetics.  Phenotypes are for hookups but genotype is forever. I wonder what romance would mean in the such world ?

I am sure no one with the right mind would want to marry a complete stranger. Dating is our way to get to know more (and also to be known) about our potential mates. Yes of course typically we would show our best sides while dating but with time eventually we expect to see more of the real side of our potential mates. We would know their siblings, parents, friends, pets, etc. 

Hence we do select our partner, carefully in some sense. This is non un-romantic at all. Marriage is no walk in the park. Life is not always easy. Storms would eventually come. Hence the question of being committed to each other -no matter what- is essential. Implicit in traditional marriage is the promise of 'till death do us part. I am anyone would agree that it would be more enjoyable to share our life (and we life but once) with someone that is compatible with us. 

In that context the whole-genome sequencing would completely make sense. Are we genetically compatible ? Is there a possibility that the offspring would have a lethal disease when our genes combine? It might sounds un-romantic at first but it is completely logical if we consider that after all we all want to life happily ever after.  


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